This netcast explores the rapidely changing world of biotech, with a penchant towards getting a better understanding of who we are and where we are going. The living world will soon be a true substrate for engineering. Our world will change, and so will we. We bring a first hand account from the scientists that are moving us into this new technological era - the era of biotech. Produced by Marc Pelletier and Leo Laporte @ TWiT.Tv
There are currently 26 episodes from June 2006 to today! To listen to the videos
Click on the embeded audio players below. But note that only 2009-2008 videos are shown. To get to the older episodes you will have to http://www.twit.tv/FIB
PART 1 of 2: Futures in Biotech 37: Just A Touch Of Green - Published on Dec 29, 2008 GREEN FLUORESCENT PROTEIN DISCOVERY and HOW ORGANISMS SENSE TOUCH
Marty Chalfie, 2008 Nobel Laureate in Chemistry This episode covers how Marty Chalfie discovered the molecular machinery that senses touch. In Part II, Chalfie describes how he developed one of the most important tools of modern molecular biology, one that allows us to see inside a living cells, down to the protein level. With green fluorescent protein, or GFP, we can now track the life of a protein, from when the gene that makes the protein is turned on, to where it goes, to where it dies. Audible Pick: The Snows of Kilimanjaro and Other Stories, Abridged, By Ernest Hemingway, Narrated by Stacy Keach. Transcripts to the shows are now available on the FiB Extras blog thanks tom.price@podsinprint.com, PodsinPrint Also thanks to Phil Pelletier and Will Hall for the great themes. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 57:56
PART 2 of 2: Futures in Biotech 38: It Is Easy Being Green - Published on Jan 31, 2009
PART 2: Dr. Martin Chalfie; Professor and Chair of the Department of Biological Sciences, Colombia University, New York, NY. This is Part II of our conversation with Dr. Martin Chalfie. In this episode Dr. Chalfie shares the historical account of his contribution to the 2008 Nobel Prize in Chemistry: How he transformed a green fluorescent jellyfish protein into the most important biological marker used today, one that allows us to track the life of recombinant protein in a living cell. 2008 Nobel Prize in Chemistry Interview with Awardees Audible pick: The Ten Most Beautiful Experiments, by George Johnson, Narrated by dion Graham. To sign up for a free audiobook, visit Audible.com/biotech. Transcripts to the shows are now available on the FiB Extras blog thanks tom.price@podsinprint.com, PodsinPrint Also thanks to Phil Pelletier and Will Hall for the great themes. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 51:40
Futures in Biotech 36: Avoiding Death, Not Taxes with Dr. Cynthia Kenyon
Published on Nov 24, 2008
Host: Marc Pelletier Guest: Dr. Cynthia Kenyon; Professor, Department of Biochemistry and Biophysics, University of California San Francisco, Director of the Larry L. Hillblom Center for the Biology of Aging. We are back into a world leading lab to discuss the genetics of aging. Can it be controlled? You bet, and the implications are enormous. When these findings translate to the clinic, it will truly be a game changer for humanity. Some interesting links: sirtrispharma Elixir Sirtris Audible Pick: Prey by Michael Crichton. For a 30 day free trial visit GotoMeeting Transcripts to the shows are now available on the FiB Extras blog thanks tom.price@podsinprint.com, PodsinPrint Also thanks to Phil Pelletier and Will Hall for the great themes. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 1:01:21
Futures in Biotech 35: The Brain Machine Interface
Published on Oct 27, 2008
Host: Marc Pelletier Dr. Justin Sanchez discusses technologies that enable direct brain to computer interfacing, just think… Guest: Dr. Justin C. Sanchez, Director of the Neuroprosthetics Research Group, Assistant Professor, Department of Pediatrics, Division of Neurology, Department of Neuroscience, Department of Biomedical Engineering, University of Florida. I really had no idea that the technologies that Justin has developed existed other than in science fiction. The possibilities are endless, and could change everything from computing, to flying planes, to simply changing the channel… I will keep these notes short, and let Justin explain. Find more, including videos at: The Neuroprosthetics Research Group Transcripts to the shows are now available on the FiB Extras blog thanks tom.price@podsinprint.com, PodsinPrint. Also thanks to Phil Pelletier and Will Hall for the great themes. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 50:11
Futures in Biotech 34: A Great Historical Document - The Human Genome
Published on Sep 12, 2008
Host: Marc Pelletier Mark Gerstein endeavors to make sense our genome on its past and present course. Guest: Mark Gerstein, the Albert L. Williams Professor of Biomedical Informatics, a professor of Molecular Biophysics and Biochemistry and professor of Computer Science at Yale University Gerstein Lab. In past shows, we've had Lee hood, the inventor of the DNA sequencer, and George Church who was among those personally involved in initiating the Human project. But getting the code and really understanding these human blueprints are entirely different problems. Our guest today, Mark Gerstein, is trying to make sense of it all, and his work amoung other things has revealed that the genome is more than just a blueprint, or list of parts, but a rich historical text about our past. BLAST this sequence: atgttcc tgtccttccc caccaccaag acctacttcc cgcacttcga cctgagccac ggctctgccc aggttaaggg ccacggcaag aaggtggccg acgcgctgac caacgccgtg gcgcacgtgg acgacatgcc caacgcgctg tccgccctga gcgacctgca cgcgcacaag cttcgggtgg acccggtcaa cttcaagctc ctaa Instructions: Copy and Paste the DNA sequence into the query window, and hit the blast button. What does this encode? Interesting: Try again selecting the NON-HUMAN database. What organism is the exact same gene found in? Why? Audible pick of the week: Legacy of Ashes: The History of the CIA, Unabridged, By Tim Weiner, Narrated by Stefan Rudnicki. For your free audio book visit Audible.com/biotech. TWiT T-Shirts from Lori LeBeau Walsh. Transcripts to the shows are now available on the FiB Blog thanks to the kind folks at PodsinPrint. Also thanks to Philippe Pelletier and Will Hall for the great themes. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 55:35
Futures in Biotech 33: Dr. Milner’s Explorations Into The Human Mind
Published on Jul 23, 2008
Host: Marc Pelletier Dr. Brenda Milner describes the experiments that led to a revolution in modern neuroscience. Guest: Dr. Brenda Milner; Dorothy J. Killam Professor of Psychology, Montreal Neurological Institute and Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada. Throughout her 58 years at the Montreal Neurological Institute, Dr. Milner has explored the inner workings of the human mind, and helped define the structures that give us our exquisite memory and ability for leaning. Her groundbreaking work has influenced generations of psychologists and neuroscientists, and through her unbridled curiosity has revealed many facets to the human mind that were previously unknown. Gairdner Foundation Gairdner News Dr. Milner on Wikipedia Audible pick of the week: Starswarm by Dr. Jerry Pournelle, narrated by Lloyd James. For your free audio book visit Audible.com/biotech. Transcripts to the shows are now available on the FiB Blog thanks to the kind folks at PodsinPrint. Thanks to Cachefly for providing the bandwidth for this netcast. Running time: 1:12:37
Futures in Biotech 32: Controlling HIV Evolution
Published on Jun 07, 2008
Host: Marc Pelletier Dr. Ronald Collman talks about exciting new discoveries on HIV, the virus that has taken 25 million lives. Guest: Dr. Ronald Collman, professor of medicine in microbiology, virus/cell/molecular core director, Penn Center for AIDS Research, University of Pennsylvania. It looks like the summer of 2008 will be an amazing summer for science. The Phoenix Mars Mission and NASA have successfully landed their probe on the Martian arctic, in search for the conditions that can sustain life (FiB24), the personal genome project, run by Dr. George Church, is braving us forward into a new era human genomics (FiB29), and lastly, the Large Hadron Collider (LHC) is getting readied to explore the origins of the Big Bang, and may just unravel the ultimate theory of everything (FiB31). Nevertheless, a large cloud hangs over humanity, which has taken over 25 million lives (warning: hardcore biotech discussion). Dr. Ronald Collman describes the molecular structure, pathology, and with great insight, the incredible discoveries that might just help us conquer HIV. Software pick: Papers Audible pick: Freakonomics: A Rogue Economist Explores the Hidden Side of Everything by Steven D. Levitt and Stephen J. Dubner. For your free audio book visit Audible.com/biotech. Transcripts to the shows are now available on the FiB Blog thanks to the kind folks at PodsinPrint Thanks to Cachefly for providing the bandwidth for this netcast. Also thanks to Will Hall for the great theme. Running time: 49:46
Futures in Biotech 31: The Eensy-Weensy Teenie Weenie Big Bang
Published on May 03, 2008
Host: Marc Pelletier Guest: Dr. Michio Kaku, Henry Semat Professor of Theoretical Physics at the Graduate Center of the City University of New York. In this episode, we are very fortunate to have Dr. Michio Kaku. He is the co-founder of String Field Theory, and a Professor of Theoretical Physics at City Univerity in NY. In our discussion he talks about everything, literally: the theory of EVERYTHING! I must say, if we are going to have a true understanding of the living world, it will demand an understanding our universe and how it 's assembled. You can't separate out the laws of physics from biology, they go hand in hand. Dr. Kaku also talks about the current teleportation experiments to the space shuttle, and how we might some day be able to teleport DNA. Seriously, that is some BIOTECH!!! Dr. Kaku's Book: Physics of the Impossible: A Scientific Exploration into the World of Phasers, Force Fields, Teleportation, and Time Travel Our Audible Pick of the week: Born Standing UP: A Comic's Life by Steve Martin. For your free audio book visit Audible.com/biotech. Transcripts to the shows are now available on the FiB Blog thanks to the kind folks at PodsinPrint Thanks to Cachefly for providing the bandwidth for this netcast. Also thanks to Will Hall for the great theme. Running time: 54:23
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