Monday, March 17, 2014

Fruit flies help uncover tumor-preventing protein complex

Fruit flies help uncover tumor-preventing protein complex
Pictured here are ectopic neural stem cells formed from dedifferentiation of progenitor cells upon loss of both HDAC3 and Snr1 (a subunit of the Brahma complex). Credit: Chwee Tat Koe
A team of researchers from Duke-NUS Graduate Medical School have discovered a protein complex that disrupts the process known as dedifferentiation, known to promote tumor development.
Dedifferentiation (reversion) is a process that leads progenitor or  to become 'ectopic neural stem cells' which causes tumors. By detecting this protein complex, Duke-NUS researchers have shed light on a process that inhibits  and gives hope for the discovery of therapies and treatments that target tumor prevention through this pathway.

http://phys.org/news/2014-03-fruit-flies-uncover-tumor-preventing-protein.html

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