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Thursday, February 20, 2014
WONDERFUL NEWS! Cell Therapy achieves complete remission in patients with End-Stage Leukemia - Research team led by Michel Sadelain at Memorial Sloan Kettering Cancer Center
Led by Michel Sadelain at Memorial Sloan Kettering Cancer Center, a recent clinical trial for a cell therapy treatment for adult B-cell acute lymphoblastic leukemia, or B-ALL, showed nearly 90 percent achieved complete remission of the disease. This was reported in Science Translational Medicine.
"Cell therapy refers to a new, very promising way of treating cancer. Also sometimes called immunotherapy, it involves genetically modifying patients’ T cells so that they use a particular biological marker to identify and destroy cancer cells, which the immune system doesn’t generally recognize as a threat. “If you take a pill or chemical, once you’ve given the pill, that’s what you’ve got and then it’s eliminated, and you can’t go too high because it sometimes gets toxic. In this case, the T cells are stimulated by the cancer. It’s a treatment that we only give once and then they proliferate. It’s what we call a ‘living drug,’” Sadelain told Singularity Hub."