Saturday, February 21, 2009

Blood cell birth

Fluorescence imaging technology lets us see the inner workings of Blood cell birth.

Cells with clear endothelial morphology shown giving rise to blood cells. Left panel: phase contrast. Right panel: fluorescence detecting HIstone 2B-Venues expression.

1st pause in video: single mesodermal cell starting the colony
2nd pause: all cells in the colony exhibit a clear endothelial sheet mrophology
3rd pause: some cells lose tight integration into the endothelial sheet but keep adhering to endothelial cells
4th pause: Blood cells detach and are free-floating.

The arrow is following the starting cell and one daughter cell after each cell division until the end of the video

No comments:

Post a Comment